BDBM384215 (4S)-8-[3-(2-amino- 5-chloropyridin-4- yl)-1H-pyrazolo[3,4- b]pyrazin-6-yl]-2- oxa-8-azaspiro[4.5]- decan-4-amine::US10280171, Example 137::US10851110, Example 137::US11466017, Example 137
SMILES N[C@@H]1COCC11CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cc(N)ncc1Cl
InChI Key
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 384215
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
The University of Texas System
US Patent
The University of Texas System
US Patent
Affinity DataIC50: 1.03E+3nMAssay Description:KYSE-520 cells (10 k cells/well) were grown in 384-well plate in 20 uL of medium (RPMI-1640, without phenol red, containing 10% FBS) at 37° C. with 5...More data for this Ligand-Target Pair